Name: Shivani Tanna

Theme: Multiple Myeloma

OPTION LIST

A	Osteoclasts	I
B	Inflammation	J
C	Osteoblasts	K
D	Amyloid	L
E	Extramedullary tumour deposits	M
F	Bence-Jones proteins	N
G	Barry-Jane proteins	O
H	Paraprotein	P

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

1. Free light chains produced by abnormal plasma cells that are

small enough to pass into the urine.

2. Found in patients with Myeloma with low serum albumin and

oedema.

3. A reactive increase in number of plasma cells in the marrow and

polyclonal increase in Igs.

4. A monoclonal immunoglobulin which appears as a dense

narrow band (M band) on electrophoresis.

5. Stimulated by IL-6 secreted by cells in the vicinity of the

myeloma cells. Produces radiological changes resembling those

of generalized osteoporosis.

ANSWERS

1. F

2. D

3. B

4. H

5. A